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A traditional gynecological medicine inhibits ovarian cancer progression and eliminates cancer stem cells via the LRPPRC–OXPHOS axis

BACKGROUND: Ovarian cancer (OC) is the most lethal malignant gynecological tumor type for which limited therapeutic targets and drugs are available. Enhanced mitochondrial oxidative phosphorylation (OXPHOS), which enables cell growth, migration, and cancer stem cell maintenance, is a critical driver...

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Detalles Bibliográficos
Autores principales: Jiang, Ruibin, Chen, Zhongjian, Ni, Maowei, Li, Xia, Ying, Hangjie, Fen, Jianguo, Wan, Danying, Peng, Chanjuan, Zhou, Wei, Gu, Linhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373366/
https://www.ncbi.nlm.nih.gov/pubmed/37496051
http://dx.doi.org/10.1186/s12967-023-04349-3