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A traditional gynecological medicine inhibits ovarian cancer progression and eliminates cancer stem cells via the LRPPRC–OXPHOS axis
BACKGROUND: Ovarian cancer (OC) is the most lethal malignant gynecological tumor type for which limited therapeutic targets and drugs are available. Enhanced mitochondrial oxidative phosphorylation (OXPHOS), which enables cell growth, migration, and cancer stem cell maintenance, is a critical driver...
Autores principales: | Jiang, Ruibin, Chen, Zhongjian, Ni, Maowei, Li, Xia, Ying, Hangjie, Fen, Jianguo, Wan, Danying, Peng, Chanjuan, Zhou, Wei, Gu, Linhui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373366/ https://www.ncbi.nlm.nih.gov/pubmed/37496051 http://dx.doi.org/10.1186/s12967-023-04349-3 |
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