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IRAK inhibitor can improve insulin sensitivity in insulin-resistant mice fed with a high-fat diet

BACKGROUND: Obesity and the inflammation associated with it, play a key role in the development of insulin resistance through the release of inflammatory cytokines and free fatty acids and the stimulation of toll-like receptors (TLR). Interleukin-1 receptor-associated kinase (IRAK), which mediates t...

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Detalles Bibliográficos
Autores principales: Allahyari, Mostafa, Rajaie, Athena, Fallah, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373392/
https://www.ncbi.nlm.nih.gov/pubmed/37551306
http://dx.doi.org/10.1515/abm-2020-0034