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Insights into the Structure of Comirnaty Covid-19 Vaccine: A Theory on Soft, Partially Bilayer-Covered Nanoparticles with Hydrogen Bond-Stabilized mRNA–Lipid Complexes

[Image: see text] Despite the worldwide success of mRNA-LNP Covid-19 vaccines, the nanoscale structures of these formulations are still poorly understood. To fill this gap, we used a combination of atomic force microscopy (AFM), dynamic light scattering (DLS), transmission electron microscopy (TEM),...

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Detalles Bibliográficos
Autores principales: Szebeni, János, Kiss, Bálint, Bozó, Tamás, Turjeman, Keren, Levi-Kalisman, Yael, Barenholz, Yechezkel, Kellermayer, Miklós
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373524/
https://www.ncbi.nlm.nih.gov/pubmed/37417667
http://dx.doi.org/10.1021/acsnano.2c11904