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SARS-CoV-2 nsp13 Restricts Episomal DNA Transcription without Affecting Chromosomal DNA

Nonstructural protein 13 (nsp13), the helicase of SARS-CoV-2, has been shown to possess multiple functions that are essential for viral replication, and is considered an attractive target for the development of novel antivirals. We were initially interested in the interplay between nsp13 and interfe...

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Detalles Bibliográficos
Autores principales: Li, Aixin, Zhang, Bei, Zhao, Kaitao, Yin, Zhinang, Teng, Yan, Zhang, Lu, Xu, Zaichao, Liang, Kaiwei, Cheng, Xiaoming, Xia, Yuchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373537/
https://www.ncbi.nlm.nih.gov/pubmed/37347173
http://dx.doi.org/10.1128/jvi.00512-23