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Enhanced Virus Translation Enables miR-122-Independent Hepatitis C Virus Propagation

The 5′ untranslated region (UTR) of the hepatitis C virus (HCV) genome forms RNA structures that regulate virus replication and translation. The region contains an internal ribosomal entry site (IRES) and a 5′-terminal region. Binding of the liver-specific microRNA (miRNA) miR-122 to two binding sit...

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Detalles Bibliográficos
Autores principales: Panigrahi, Mamata, Palmer, Michael A., Wilson, Joyce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373559/
https://www.ncbi.nlm.nih.gov/pubmed/37338370
http://dx.doi.org/10.1128/jvi.00858-21