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Knockdown of KLF5 ameliorates renal fibrosis in MRL/lpr mice via inhibition of MX1 transcription

OBJECTIVE: This study aims to elucidate the role of Kruppel‐like factor (KLF5) and myxovirus resistance 1 (MX1) in the progression of renal fibrosis in lupus nephritis (LN). METHODS: First, the expression of KLF5 and MX1 was assessed in the peripheral blood of LN patients and healthy participants. N...

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Detalles Bibliográficos
Autores principales: Tao, Shanshan, Tan, Xiao, Chai, Wen, Peng, Xiaojie, Zheng, Weimin, Fu, Rui, Deng, Meihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373570/
https://www.ncbi.nlm.nih.gov/pubmed/37506140
http://dx.doi.org/10.1002/iid3.937