Why are G-quadruplexes good at preventing protein aggregation?

Maintaining a healthy protein folding environment is essential for cellular function. Recently, we found that nucleic acids, G-quadruplexes in particular, are potent chaperones for preventing protein aggregation. With the aid of structure-function and NMR analyses of two G-quadruplex forming sequenc...

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Detalles Bibliográficos
Autores principales: Litberg, Theodore J., Sannapureddi, Rajesh Kumar Reddy, Huang, Zijue, Son, Ahyun, Sathyamoorthy, Bharathwaj, Horowitz, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373610/
https://www.ncbi.nlm.nih.gov/pubmed/37493593
http://dx.doi.org/10.1080/15476286.2023.2228572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373610/
https://www.ncbi.nlm.nih.gov/pubmed/37493593
http://dx.doi.org/10.1080/15476286.2023.2228572

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