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Why are G-quadruplexes good at preventing protein aggregation?
Maintaining a healthy protein folding environment is essential for cellular function. Recently, we found that nucleic acids, G-quadruplexes in particular, are potent chaperones for preventing protein aggregation. With the aid of structure-function and NMR analyses of two G-quadruplex forming sequenc...
Autores principales: | Litberg, Theodore J., Sannapureddi, Rajesh Kumar Reddy, Huang, Zijue, Son, Ahyun, Sathyamoorthy, Bharathwaj, Horowitz, Scott |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373610/ https://www.ncbi.nlm.nih.gov/pubmed/37493593 http://dx.doi.org/10.1080/15476286.2023.2228572 |
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