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Phosphorylation of the N-terminus of Syntaxin-16 controls interaction with mVps45 and GLUT4 trafficking in adipocytes

The ability of insulin to stimulate glucose transport in muscle and fat cells is mediated by the regulated delivery of intracellular vesicles containing glucose transporter-4 (GLUT4) to the plasma membrane, a process known to be defective in disease such as Type 2 diabetes. In the absence of insulin...

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Detalles Bibliográficos
Autores principales: Bremner, Shaun K., Berends, Rebecca, Kaupisch, Alexandra, Roccisana, Jennifer, Sutherland, Calum, Bryant, Nia J., Gould, Gwyn W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373645/
https://www.ncbi.nlm.nih.gov/pubmed/37520260
http://dx.doi.org/10.7717/peerj.15630