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What are the treatment remission, response and extent of improvement rates after up to four trials of antidepressant therapies in real-world depressed patients? A reanalysis of the STAR*D study’s patient-level data with fidelity to the original research protocol

OBJECTIVE: Reanalyse the patient-level data set of the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study with fidelity to the original research protocol and related publications. DESIGN: The study was open label and semirandomised examining the effectiveness of up to four optimis...

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Detalles Bibliográficos
Autores principales: Pigott, H Edmund, Kim, Thomas, Xu, Colin, Kirsch, Irving, Amsterdam, Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373710/
https://www.ncbi.nlm.nih.gov/pubmed/37491091
http://dx.doi.org/10.1136/bmjopen-2022-063095