Osthole/borneol thermosensitive gel via intranasal administration enhances intracerebral bioavailability to improve cognitive impairment in APP/PS1 transgenic mice

Alzheimer’s disease (AD) poses a significant threat to the global elderly population. Traditional Chinese medicine (TCM) has been widely utilized in the treatment of AD. Osthole, a bioactive ingredient classified as an “emperor” in many TCM formulas, has been demonstrated to effectively alleviate AD...

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Detalles Bibliográficos
Autores principales: Wu, Fanchang, Huang, Mingjun, Zuo, Xue, Xie, Ruiye, Liu, Jinman, Ke, Junyu, Li, Weirong, Wang, Qi, Liang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373789/
https://www.ncbi.nlm.nih.gov/pubmed/37521471
http://dx.doi.org/10.3389/fphar.2023.1224856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373789/
https://www.ncbi.nlm.nih.gov/pubmed/37521471
http://dx.doi.org/10.3389/fphar.2023.1224856

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