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Case Report: Genetic and immune microenvironmental characteristics of a rectal cancer patient with MSS/PD-L1-negative recurrent hepatopulmonary metastasis who achieved complete remission after treatment with PD-1 inhibitor

Currently, microsatellite high instability (MSI-H)/mismatch repair protein deletion (dMMR) has become a crucial biomarker for utilizing immune checkpoint inhibitors in patients with advanced colorectal cancer (mCRC). However, the proportion of MSI-H/dMMR in advanced patients is only about 5% and mCR...

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Detalles Bibliográficos
Autores principales: Song, Yang, Long, Juan, Su, Xiaona, Chen, Zhuo, He, Yue, Shao, Weikang, Wang, Bin, Chen, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373867/
https://www.ncbi.nlm.nih.gov/pubmed/37520536
http://dx.doi.org/10.3389/fimmu.2023.1197543