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Antineoplastic effects of sodium dichloroacetate and omeprazole, alone or in combination, on canine oral mucosal melanoma cells

Oral mucosal melanoma (OMM) is a common neoplasm in canines, although it is rare in humans. Cancer cells present alterations in energetic metabolism, and the Warburg effect states that most cancer cells undergo aerobic glycolysis. This can be reversed by certain drugs, resulting in decreased cell vi...

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Detalles Bibliográficos
Autores principales: Toledo, Gabriela F., Nagamine, Marcia K., Nowosh, Victor, Machado, Felippe T., Massoco, Cristina O., Souza-Pinto, Nadja C., Dagli, Maria L. Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373870/
https://www.ncbi.nlm.nih.gov/pubmed/37520008
http://dx.doi.org/10.3389/fvets.2023.1186650