CRISPR library screening to develop HEK293-derived cell lines with improved lentiviral vector titers

Lentiviral (LV) vectors have emerged as powerful tools for treating genetic and acquired human diseases. As clinical studies and commercial demands have progressed, there has been a growing need for large amounts of purified LV vectors. To help meet this demand, we developed CRISPR library screening...

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Detalles Bibliográficos
Autores principales: Iaffaldano, Brian J., Marino, Michael P., Reiser, Jakob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genome Editing
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373892/
https://www.ncbi.nlm.nih.gov/pubmed/37520398
http://dx.doi.org/10.3389/fgeed.2023.1218328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373892/
https://www.ncbi.nlm.nih.gov/pubmed/37520398
http://dx.doi.org/10.3389/fgeed.2023.1218328

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