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CRISPR library screening to develop HEK293-derived cell lines with improved lentiviral vector titers
Lentiviral (LV) vectors have emerged as powerful tools for treating genetic and acquired human diseases. As clinical studies and commercial demands have progressed, there has been a growing need for large amounts of purified LV vectors. To help meet this demand, we developed CRISPR library screening...
Autores principales: | Iaffaldano, Brian J., Marino, Michael P., Reiser, Jakob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373892/ https://www.ncbi.nlm.nih.gov/pubmed/37520398 http://dx.doi.org/10.3389/fgeed.2023.1218328 |
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