A heterotrimeric complex of Toxoplasma proteins promotes parasite survival in interferon gamma-stimulated human cells

Toxoplasma gondii secretes protein effectors to subvert the human immune system sufficiently to establish a chronic infection. Relative to murine infections, little is known about which parasite effectors disarm human immune responses. Here, we used targeted CRISPR screening to identify secreted pro...

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Detalles Bibliográficos
Autores principales: Lockyer, Eloise J., Torelli, Francesca, Butterworth, Simon, Song, Ok-Ryul, Howell, Steven, Weston, Anne, East, Philip, Treeck, Moritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373997/
https://www.ncbi.nlm.nih.gov/pubmed/37459303
http://dx.doi.org/10.1371/journal.pbio.3002202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373997/
https://www.ncbi.nlm.nih.gov/pubmed/37459303
http://dx.doi.org/10.1371/journal.pbio.3002202

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