HIV-1 virological synapse formation enhances infection spread by dysregulating Aurora Kinase B

HIV-1 spreads efficiently through direct cell-to-cell transmission at virological synapses (VSs) formed by interactions between HIV-1 envelope proteins (Env) on the surface of infected cells and CD4 receptors on uninfected target cells. Env-CD4 interactions bring the infected and uninfected cellular...

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Detalles Bibliográficos
Autores principales: Bruce, James W., Park, Eunju, Magnano, Chris, Horswill, Mark, Richards, Alicia, Potts, Gregory, Hebert, Alexander, Islam, Nafisah, Coon, Joshua J., Gitter, Anthony, Sherer, Nathan, Ahlquist, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374047/
https://www.ncbi.nlm.nih.gov/pubmed/37459363
http://dx.doi.org/10.1371/journal.ppat.1011492