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Competition among variants is predictable and contributes to the antigenic variation dynamics of African trypanosomes

Several persistent pathogens employ antigenic variation to continually evade mammalian host adaptive immune responses. African trypanosomes use variant surface glycoproteins (VSGs) for this purpose, transcribing one telomeric VSG expression-site at a time, and exploiting a reservoir of (sub)telomeri...

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Detalles Bibliográficos
Autores principales: Escrivani, Douglas O., Scheidt, Viktor, Tinti, Michele, Faria, Joana, Horn, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374056/
https://www.ncbi.nlm.nih.gov/pubmed/37459347
http://dx.doi.org/10.1371/journal.ppat.1011530