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Competition among variants is predictable and contributes to the antigenic variation dynamics of African trypanosomes
Several persistent pathogens employ antigenic variation to continually evade mammalian host adaptive immune responses. African trypanosomes use variant surface glycoproteins (VSGs) for this purpose, transcribing one telomeric VSG expression-site at a time, and exploiting a reservoir of (sub)telomeri...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374056/ https://www.ncbi.nlm.nih.gov/pubmed/37459347 http://dx.doi.org/10.1371/journal.ppat.1011530 |