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A comprehensive protein interaction map and druggability investigation prioritized dengue virus NS1 protein as promising therapeutic candidate

Dengue Virus (DENV) is a serious threat to human life worldwide and is one of the most dangerous vector-borne diseases, causing thousands of deaths annually. We constructed a comprehensive PPI map of DENV with its host Homo sapiens and performed various bioinformatics analyses. We found 1195 interac...

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Detalles Bibliográficos
Autores principales: Farooq, Qurrat ul Ain, Aiman, Sara, Ali, Yasir, Shaukat, Zeeshan, Khan, Asifullah, Samad, Abdus, Wadood, Abdul, Li, Chunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374080/
https://www.ncbi.nlm.nih.gov/pubmed/37498862
http://dx.doi.org/10.1371/journal.pone.0287905