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On the feasibility of using TCR sequencing to follow a vaccination response – lessons learned

T cells recognize pathogens by their highly specific T-cell receptor (TCR), which can bind small fragments of an antigen presented on the Major Histocompatibility Complex (MHC). Antigens that are provided through vaccination cause specific T cells to respond by expanding and forming specific memory...

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Detalles Bibliográficos
Autores principales: de Greef, Peter C., Lanfermeijer, Josien, Hendriks, Marion, Cevirgel, Alper, Vos, Martijn, Borghans, José A. M., van Baarle, Debbie, de Boer, Rob J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374308/
https://www.ncbi.nlm.nih.gov/pubmed/37520553
http://dx.doi.org/10.3389/fimmu.2023.1210168