Recombinant BCG expressing the LTAK63 adjuvant increased memory T cells and induced long-lasting protection against Mycobacterium tuberculosis challenge in mice

Vaccine-induced protection against Mycobacterium tuberculosis (Mtb) is usually ascribed to the induction of Th1, Th17, and CD8(+) T cells. However, protective immune responses should also involve other immune cell subsets, such as memory T cells. We have previously shown improved protection against...

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Detalles Bibliográficos
Autores principales: Marques-Neto, Lázaro Moreira, Trentini, Monalisa Martins, Kanno, Alex Issamu, Rodriguez, Dunia, Leite, Luciana Cezar de Cerqueira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374402/
https://www.ncbi.nlm.nih.gov/pubmed/37520577
http://dx.doi.org/10.3389/fimmu.2023.1205449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374402/
https://www.ncbi.nlm.nih.gov/pubmed/37520577
http://dx.doi.org/10.3389/fimmu.2023.1205449

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