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Recombinant BCG expressing the LTAK63 adjuvant increased memory T cells and induced long-lasting protection against Mycobacterium tuberculosis challenge in mice
Vaccine-induced protection against Mycobacterium tuberculosis (Mtb) is usually ascribed to the induction of Th1, Th17, and CD8(+) T cells. However, protective immune responses should also involve other immune cell subsets, such as memory T cells. We have previously shown improved protection against...
Autores principales: | Marques-Neto, Lázaro Moreira, Trentini, Monalisa Martins, Kanno, Alex Issamu, Rodriguez, Dunia, Leite, Luciana Cezar de Cerqueira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374402/ https://www.ncbi.nlm.nih.gov/pubmed/37520577 http://dx.doi.org/10.3389/fimmu.2023.1205449 |
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