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Dissecting the conformational complexity and mechanism of a bacterial heme transporter

Iron-bound cyclic tetrapyrroles (hemes) are redox-active cofactors in bioenergetic enzymes. However, the mechanisms of heme transport and insertion into respiratory chain complexes remain unclear. Here, we used cellular, biochemical, structural and computational methods to characterize the structure...

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Detalles Bibliográficos
Autores principales: Wu, Di, Mehdipour, Ahmad R., Finke, Franziska, Goojani, Hojjat G., Groh, Roan R., Grund, Tamara N., Reichhart, Thomas M. B., Zimmermann, Rita, Welsch, Sonja, Bald, Dirk, Shepherd, Mark, Hummer, Gerhard, Safarian, Schara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374445/
https://www.ncbi.nlm.nih.gov/pubmed/37095238
http://dx.doi.org/10.1038/s41589-023-01314-5