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Development of a DNA aptamer targeting IDO1 with anti-tumor effects

Immune checkpoint blockade has become an effective approach to reverse the immune tolerance of tumor cells. Indoleamine 2,3-dioxygenase 1 (IDO1) is frequently upregulated in many types of cancers and contributes to the establishment of an immunosuppressive cancer microenvironment, which has been tho...

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Detalles Bibliográficos
Autores principales: Zhu, Zhenyu, Yang, Zeliang, Zhu, Chuanda, Hu, Zixi, Jiang, Zhongyu, Gong, Jingjing, Yuan, Yuyao, Chen, Xi, Jin, Yan, Yin, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374466/
https://www.ncbi.nlm.nih.gov/pubmed/37520707
http://dx.doi.org/10.1016/j.isci.2023.107367