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Exploring the Binding Mechanism of NRG1–ERBB3 Complex and Discovery of Potent Natural Products to Reduce Diabetes-Assisted Breast Cancer Progression

Diabetes mellitus significantly contributes to breast cancer progression, where hyperglycemia upregulates specific genes, leading to more aggressive tumor growth. In patients with BC that develop diabetes, neuregulin 1 (NRG1) and epidermal growth factor receptor 3 (ERBB3) overexpression exacerbate t...

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Detalles Bibliográficos
Autores principales: Marafie, Sulaiman K., Alshawaf, Eman, Abu-Farha, Mohamed, Thanaraj, Thangavel Alphonse, Wei, Dong-Qing, Al-Mulla, Fahd, Khan, Abbas, Abubaker, Jehad, Mohammad, Anwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374477/
https://www.ncbi.nlm.nih.gov/pubmed/37389721
http://dx.doi.org/10.1007/s12539-023-00566-y