EpCAM tumor specificity and proteoform patterns in urothelial cancer

BACKGROUND: The role of the epithelial cell adhesion molecule (EpCAM) in cancer is still unclear. EpCAM cleavage through regulated intramembrane proteolysis results in fragments which interact with both oncogenic and tumor suppressive pathways. Additionally, the EpCAM molecule itself is used as a de...

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Detalles Bibliográficos
Autores principales: Dressler, Franz F., Hinrichs, Sofie, Roesch, Marie C., Perner, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374485/
https://www.ncbi.nlm.nih.gov/pubmed/37154925
http://dx.doi.org/10.1007/s00432-023-04809-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374485/
https://www.ncbi.nlm.nih.gov/pubmed/37154925
http://dx.doi.org/10.1007/s00432-023-04809-9

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