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Artesunate alleviates 5-fluorouracil-induced intestinal damage by suppressing cellular senescence and enhances its antitumor activity

BACKGROUND: Colorectal cancer (CRC) is one of the most prevalent diagnosed malignancies and one of the leading causes of cancer-related deaths worldwide. 5-Fluorouracil (5-FU) and its combination regimen are commonly used as primary chemotherapeutic agents for advanced CRC. Intestinal mucositis is o...

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Detalles Bibliográficos
Autores principales:	Xia, Jing, Dai, Qian long, He, Siyue, Jia, Hui-jie, Liu, Xian-Guo, Hua, Hui, Zhou, Min, Wang, Xiaobo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374509/ https://www.ncbi.nlm.nih.gov/pubmed/37498338 http://dx.doi.org/10.1007/s12672-023-00747-7

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