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Quinpirole ameliorates nigral dopaminergic neuron damage in Parkinson’s disease mouse model through activating GHS-R1a/D(2)R heterodimers

Growth hormone secretagogue receptor 1a (GHS-R1a) is an important G protein-coupled receptor (GPCR) that regulates a variety of functions by binding to ghrelin. It has been shown that the dimerization of GHS-R1a with other receptors also affects ingestion, energy metabolism, learning and memory. Dop...

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Detalles Bibliográficos
Autores principales: Tang, Ting-ting, Bi, Ming-xia, Diao, Mei-ning, Zhang, Xiao-yi, Chen, Ling, Xiao, Xue, Jiao, Qian, Chen, Xi, Yan, Chun-ling, Du, Xi-xun, Jiang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374575/
https://www.ncbi.nlm.nih.gov/pubmed/36899113
http://dx.doi.org/10.1038/s41401-023-01063-0