Dietary aflatoxin B1 and antimalarial—a lumefantrine/artesunate—therapy perturbs male rat reproductive function via pro-inflammatory and oxidative mechanisms

We investigated the impact of Coartem™ (COA) and aflatoxin B1 (AFB(1)) on rats’ hypothalamus, epididymis, and testis. Male rats were randomly grouped (n = 5 rats) and treated: control group (corn oil), AFB(1) (70 µg/kg), COA (5 mg/kg), COA + AFB(1) (5 + 0.035 mg/kg) and COA + AFB(1) (5 + 0.07 mg/kg)...

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Detalles Bibliográficos
Autores principales: Owumi, Solomon E., Umez, Angel O., Arunsi, Uche, Irozuru, Chioma E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374580/
https://www.ncbi.nlm.nih.gov/pubmed/37500724
http://dx.doi.org/10.1038/s41598-023-39455-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374580/
https://www.ncbi.nlm.nih.gov/pubmed/37500724
http://dx.doi.org/10.1038/s41598-023-39455-1

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