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Dietary aflatoxin B1 and antimalarial—a lumefantrine/artesunate—therapy perturbs male rat reproductive function via pro-inflammatory and oxidative mechanisms
We investigated the impact of Coartem™ (COA) and aflatoxin B1 (AFB(1)) on rats’ hypothalamus, epididymis, and testis. Male rats were randomly grouped (n = 5 rats) and treated: control group (corn oil), AFB(1) (70 µg/kg), COA (5 mg/kg), COA + AFB(1) (5 + 0.035 mg/kg) and COA + AFB(1) (5 + 0.07 mg/kg)...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374580/ https://www.ncbi.nlm.nih.gov/pubmed/37500724 http://dx.doi.org/10.1038/s41598-023-39455-1 |