Depletion of peroxiredoxin II promotes keratinocyte apoptosis and alleviates psoriatic skin lesions via the PI3K/AKT/GSK3β signaling axis

Psoriasis is a chronic, systemic immune-mediated disease caused by abnormal proliferation, decreased apoptosis, and over-differentiation of keratinocytes. The psoriatic skin lesions due to abnormal keratinocytes are closely associated with ROS produced by inflammatory cells. Peroxiredoxin II (Prx II...

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Detalles Bibliográficos
Autores principales: Han, Ying-Hao, Feng, Lin, Lee, Seung-Jae, Zhang, Yong-Qing, Wang, Ai-Guo, Jin, Mei-Hua, Sun, Hu-Nan, Kwon, Taeho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374606/
https://www.ncbi.nlm.nih.gov/pubmed/37500620
http://dx.doi.org/10.1038/s41420-023-01566-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374606/
https://www.ncbi.nlm.nih.gov/pubmed/37500620
http://dx.doi.org/10.1038/s41420-023-01566-z

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