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Depletion of peroxiredoxin II promotes keratinocyte apoptosis and alleviates psoriatic skin lesions via the PI3K/AKT/GSK3β signaling axis

Psoriasis is a chronic, systemic immune-mediated disease caused by abnormal proliferation, decreased apoptosis, and over-differentiation of keratinocytes. The psoriatic skin lesions due to abnormal keratinocytes are closely associated with ROS produced by inflammatory cells. Peroxiredoxin II (Prx II...

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Detalles Bibliográficos
Autores principales:	Han, Ying-Hao, Feng, Lin, Lee, Seung-Jae, Zhang, Yong-Qing, Wang, Ai-Guo, Jin, Mei-Hua, Sun, Hu-Nan, Kwon, Taeho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374606/ https://www.ncbi.nlm.nih.gov/pubmed/37500620 http://dx.doi.org/10.1038/s41420-023-01566-z

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