A phase 1 study of nivolumab in combination with interferon-gamma for patients with advanced solid tumors

This phase I, dose-escalation trial evaluates the safety of combining interferon-gamma (IFN-γ) and nivolumab in patients with metastatic solid tumors. Twenty-six patients are treated in four cohorts assessing increasing doses of IFN-γ with nivolumab to evaluate the primary endpoint of safety and det...

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Detalles Bibliográficos
Autores principales: Zibelman, Matthew, MacFarlane, Alexander W., Costello, Kimberly, McGowan, Thomas, O’Neill, John, Kokate, Rutika, Borghaei, Hossein, Denlinger, Crystal S., Dotan, Efrat, Geynisman, Daniel M., Jain, Angela, Martin, Lainie, Obeid, Elias, Devarajan, Karthik, Ruth, Karen, Alpaugh, R. Katherine, Dulaimi, Essel Al-Saleem, Cukierman, Edna, Einarson, Margret, Campbell, Kerry S., Plimack, Elizabeth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374608/
https://www.ncbi.nlm.nih.gov/pubmed/37500647
http://dx.doi.org/10.1038/s41467-023-40028-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374608/
https://www.ncbi.nlm.nih.gov/pubmed/37500647
http://dx.doi.org/10.1038/s41467-023-40028-z

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