Noncanonical functions of Ku may underlie essentiality in human cells

The Ku70/80 heterodimer is a key player in non-homologous end-joining DNA repair but is involved in other cellular functions like telomere regulation and maintenance, in which Ku’s role is not fully characterized. It was previously reported that knockout of Ku80 in a human cell line results in letha...

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Detalles Bibliográficos
Autores principales: Kelly, Rachel D., Parmar, Gursimran, Bayat, Laila, Maitland, Matthew E. R., Lajoie, Gilles A., Edgell, David R., Schild-Poulter, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374653/
https://www.ncbi.nlm.nih.gov/pubmed/37500706
http://dx.doi.org/10.1038/s41598-023-39166-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374653/
https://www.ncbi.nlm.nih.gov/pubmed/37500706
http://dx.doi.org/10.1038/s41598-023-39166-7

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