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Noncanonical functions of Ku may underlie essentiality in human cells
The Ku70/80 heterodimer is a key player in non-homologous end-joining DNA repair but is involved in other cellular functions like telomere regulation and maintenance, in which Ku’s role is not fully characterized. It was previously reported that knockout of Ku80 in a human cell line results in letha...
Autores principales: | Kelly, Rachel D., Parmar, Gursimran, Bayat, Laila, Maitland, Matthew E. R., Lajoie, Gilles A., Edgell, David R., Schild-Poulter, Caroline |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374653/ https://www.ncbi.nlm.nih.gov/pubmed/37500706 http://dx.doi.org/10.1038/s41598-023-39166-7 |
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