The HDAC inhibitor domatinostat induces type I interferon α in Merkel cell carcinoma by HES1 repression

BACKGROUND: Class I selective histone deacetylase inhibitors (HDACi) have been previously demonstrated to not only increase major histocompatibility complex class I surface expression in Merkel cell carcinoma (MCC) cells by restoring the antigen processing and presentation machinery, but also exert...

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Detalles Bibliográficos
Autores principales: Srinivas, Nalini, Song, Lina, Lei, Kuan Cheok, Gravemeyer, Jan, Furtmann, Frauke, Gambichler, Thilo, Becker, Jürgen C., Sriram, Ashwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374800/
https://www.ncbi.nlm.nih.gov/pubmed/37071208
http://dx.doi.org/10.1007/s00432-023-04733-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374800/
https://www.ncbi.nlm.nih.gov/pubmed/37071208
http://dx.doi.org/10.1007/s00432-023-04733-y

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