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FTO-mediated m(6)A modification promotes malignant transformation of gastric mucosal epithelial cells in chronic Cag A(+) Helicobacter pylori infection

OBJECTIVES: Cag A(+) Helicobacter pylori chronic infection cause malignant transformation of the human gastric mucosa. N6-methyladenosine (m(6)A) modifications are the most common and abundant mRNA modifications and one of the pathways affecting tumorigenicity and tumor progression. However, the rol...

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Detalles Bibliográficos
Autores principales: Cheng, Sha, Li, Huan, Chi, Jingshu, Zhao, Wenfang, Lin, Jiahui, Liu, Xiaoming, Xu, Canxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374804/
https://www.ncbi.nlm.nih.gov/pubmed/36918410
http://dx.doi.org/10.1007/s00432-023-04684-4