Metformin promotes ferroptosis and sensitivity to sorafenib in hepatocellular carcinoma cells via ATF4/STAT3

BACKGROUND: Hepatocellular carcinoma (HCC) is a common cancer worldwide, and sorafenib is a first-line drug for the treatment of advanced liver cancer. Resistance to sorafenib has become a major challenge in the treatment of hepatocellular carcinoma, however, studies have shown that metformin can pr...

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Detalles Bibliográficos
Autores principales: Hu, Zongqiang, Zhao, Yingpeng, Li, Laibang, Jiang, Jie, Li, Wang, Mang, Yuanyi, Gao, Yang, Dong, Yun, Zhu, Jiashun, Yang, Chaomin, Ran, Jianghua, Li, Li, Zhang, Shengning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374833/
https://www.ncbi.nlm.nih.gov/pubmed/37326750
http://dx.doi.org/10.1007/s11033-023-08492-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374833/
https://www.ncbi.nlm.nih.gov/pubmed/37326750
http://dx.doi.org/10.1007/s11033-023-08492-4

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