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Metformin promotes ferroptosis and sensitivity to sorafenib in hepatocellular carcinoma cells via ATF4/STAT3
BACKGROUND: Hepatocellular carcinoma (HCC) is a common cancer worldwide, and sorafenib is a first-line drug for the treatment of advanced liver cancer. Resistance to sorafenib has become a major challenge in the treatment of hepatocellular carcinoma, however, studies have shown that metformin can pr...
Autores principales: | Hu, Zongqiang, Zhao, Yingpeng, Li, Laibang, Jiang, Jie, Li, Wang, Mang, Yuanyi, Gao, Yang, Dong, Yun, Zhu, Jiashun, Yang, Chaomin, Ran, Jianghua, Li, Li, Zhang, Shengning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374833/ https://www.ncbi.nlm.nih.gov/pubmed/37326750 http://dx.doi.org/10.1007/s11033-023-08492-4 |
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