Neuroprotective role for RORA in Parkinson’s disease revealed by analysis of post-mortem brain and a dopaminergic cell line

Parkinson’s disease (PD) is almost twice as prevalent in men, which has largely been attributed to neuroprotective effect of oestradiol in women. RORA (retinoic acid receptor-related orphan receptor alpha) regulates the transcription of central aromatase, the enzyme responsible for local oestradiol...

Descripción completa

Detalles Bibliográficos
Autores principales: Al-Zaid, Felwah S., Hurley, Michael J., Dexter, David T., Gillies, Glenda E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374904/
https://www.ncbi.nlm.nih.gov/pubmed/37500636
http://dx.doi.org/10.1038/s41531-023-00563-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374904/
https://www.ncbi.nlm.nih.gov/pubmed/37500636
http://dx.doi.org/10.1038/s41531-023-00563-4

Ejemplares similares