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In vivo and in vitro characterizations of melibiose permease (MelB) conformation-dependent nanobodies reveal sugar-binding mechanisms
Salmonella enterica serovar Typhimurium melibiose permease (MelB(St)) is a prototype of the Na(+)-coupled major facilitator superfamily transporters, which are important for the cellular uptake of molecules including sugars and small drugs. Although the symport mechanisms have been well-studied, mec...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374971/ https://www.ncbi.nlm.nih.gov/pubmed/37380079 http://dx.doi.org/10.1016/j.jbc.2023.104967 |