A comparison of the impact on neuronal transcriptome and cognition of rAAV5 transduction with three different doses in the mouse hippocampus

INTRODUCTION: Recombinant adeno-associated viruses (rAAVs) are widely used in genetic therapeutics. AAV5 has shown superior transduction efficiency, targeting neurons and glial cells in primate brains. Nonetheless, the comprehensive impact of AAV5 transduction on molecular and behavioral alterations...

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Detalles Bibliográficos
Autores principales: Liu, Yi-Si, Wang, Meng-Ling, Hu, Neng-Yuan, Li, Zi-Ming, Wu, Jia-Li, Li, Hao, Li, Jing-Ting, Li, Xiao-Wen, Yang, Jian-Ming, Gao, Tian-Ming, Chen, Yi-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375024/
https://www.ncbi.nlm.nih.gov/pubmed/37520430
http://dx.doi.org/10.3389/fnmol.2023.1195327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375024/
https://www.ncbi.nlm.nih.gov/pubmed/37520430
http://dx.doi.org/10.3389/fnmol.2023.1195327

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