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Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes

Background: Schistosoma mansoni, a parasitic worm species responsible for the neglected tropical disease schistosomiasis, undergoes strict developmental regulation of gene expression that is carefully controlled by both genetic and epigenetic processes. As inhibition of S. mansoni epigenetic machine...

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Detalles Bibliográficos
Autores principales: Padalino, Gilda, Celatka, Cassandra A., Rienhoff Jr., Hugh Y., Kalin, Jay H., Cole, Philip A., Lassalle, Damien, Forde-Thomas, Josephine, Chalmers, Iain W., Brancale, Andrea, Grunau, Christoph, Hoffmann, Karl F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375057/
https://www.ncbi.nlm.nih.gov/pubmed/37520936
http://dx.doi.org/10.12688/wellcomeopenres.18826.1