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Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes
Background: Schistosoma mansoni, a parasitic worm species responsible for the neglected tropical disease schistosomiasis, undergoes strict developmental regulation of gene expression that is carefully controlled by both genetic and epigenetic processes. As inhibition of S. mansoni epigenetic machine...
Autores principales: | Padalino, Gilda, Celatka, Cassandra A., Rienhoff Jr., Hugh Y., Kalin, Jay H., Cole, Philip A., Lassalle, Damien, Forde-Thomas, Josephine, Chalmers, Iain W., Brancale, Andrea, Grunau, Christoph, Hoffmann, Karl F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375057/ https://www.ncbi.nlm.nih.gov/pubmed/37520936 http://dx.doi.org/10.12688/wellcomeopenres.18826.1 |
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