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Semaphorin3A Exacerbates Cardiac Microvascular Rarefaction in Pressure Overload‐Induced Heart Disease

Microvascular endothelial cells (MiVECs) impair angiogenic potential, leading to microvascular rarefaction, which is a characteristic feature of chronic pressure overload‐induced cardiac dysfunction. Semaphorin3A (Sema3A) is a secreted protein upregulated in MiVECs following angiotensin II (Ang II)...

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Detalles Bibliográficos
Autores principales: Li, Chaofu, Zhao, Yongchao, Li, Fuhai, Wang, Zimu, Qiu, Zhimei, Yang, Yukun, Xiong, Weidong, Wang, Rui, Chen, Han, Xu, Fei, Zang, Tongtong, Pei, Zhiqiang, Wang, Yan, Shi, Bei, Shen, Li, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375119/
https://www.ncbi.nlm.nih.gov/pubmed/37310417
http://dx.doi.org/10.1002/advs.202206801