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Circulating immune checkpoints predict heart failure outcomes

AIMS: There are limited data examining the role of immune checkpoint (IC) ligands in the pathophysiology of heart failure (HF). Therefore, we explore this in three HF animal models and in three different human cohorts (healthy, stable, and worsening HF). METHODS AND RESULTS: Transcriptomic analyses...

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Detalles Bibliográficos
Autores principales: Screever, Elles M., Yousif, Laura I.E., Moslehi, Javid J., Salem, Joe‐Elie, Voors, Adriaan A., Silljé, Herman H.W., de Boer, Rudolf A., Meijers, Wouter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375122/
https://www.ncbi.nlm.nih.gov/pubmed/37186066
http://dx.doi.org/10.1002/ehf2.14304