Self‐Degradable Nanogels Reshape Immunosuppressive Tumor Microenvironment via Drug Repurposing Strategy to Reactivate Cytotoxic CD8(+) T Cells

Intratumoral CD8(+) T cells are crucial for effective cancer immunotherapy, but an immunosuppressive tumor microenvironment (TME) contributes to dysfunction and insufficient infiltration. Drug repurposing has successfully led to new discoveries among existing clinical drugs for use as immune modulat...

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Detalles Bibliográficos
Autores principales: Tian, Hao, Li, Wenxi, Wang, Guohao, Tian, Ye, Yan, Jie, Zhou, Songtao, Yu, Xinying, Li, Bei, Dai, Yunlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375179/
https://www.ncbi.nlm.nih.gov/pubmed/37144520
http://dx.doi.org/10.1002/advs.202301661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375179/
https://www.ncbi.nlm.nih.gov/pubmed/37144520
http://dx.doi.org/10.1002/advs.202301661

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