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Self‐Degradable Nanogels Reshape Immunosuppressive Tumor Microenvironment via Drug Repurposing Strategy to Reactivate Cytotoxic CD8(+) T Cells
Intratumoral CD8(+) T cells are crucial for effective cancer immunotherapy, but an immunosuppressive tumor microenvironment (TME) contributes to dysfunction and insufficient infiltration. Drug repurposing has successfully led to new discoveries among existing clinical drugs for use as immune modulat...
Autores principales: | Tian, Hao, Li, Wenxi, Wang, Guohao, Tian, Ye, Yan, Jie, Zhou, Songtao, Yu, Xinying, Li, Bei, Dai, Yunlu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375179/ https://www.ncbi.nlm.nih.gov/pubmed/37144520 http://dx.doi.org/10.1002/advs.202301661 |
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