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Relationship Between LTA4H Promotor Polymorphism and Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome and Its Prevention With Prednisone

The development of paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) and its prevention using prednisone may potentially be mediated by the LTA4H genotype. We assessed this hypothesis in a clinical trial evaluating prednisone to prevent TB-IRIS. We did not fin...

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Detalles Bibliográficos
Autores principales: Stek, Cari, Shey, Muki, Mnika, Khuthala, Schutz, Charlotte, Thienemann, Friedrich, Wilkinson, Robert J, Lynen, Lutgarde, Meintjes, Graeme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375423/
https://www.ncbi.nlm.nih.gov/pubmed/37520416
http://dx.doi.org/10.1093/ofid/ofad379